Ptosis Surgery in Patients with Myasthenia Gravis: A Useful Adjunct to Medical Therapy

Semin Ophthalmol. 2018;33(3):429-434. doi: 10.1080/08820538.2017.1284871. Epub 2017 Feb 22.

Abstract

Introduction: Medical management can have limitations in improving ptosis in patients with myasthenia gravis (MG). We present our experience of ptosis surgery in MG.

Materials and methods: Clinical records of all patients with MG undergoing ptosis surgery from September 2007 to November 2013 in a single center were retrospectively reviewed. Change in upper marginal reflex distance (uMRD) was the main outcome measure.

Results: Sixteen external levator advancement (ELA) procedures were performed on 11 MG patients. Fourteen of 16 procedures had pre- and postoperative uMRD documented. Thirteen of 14 procedures had improved lid height; mean increase in uMRD was 2.4 mm (P=0.0005651). Two patients required secondary lid elevation. Postoperative complications included more noticeable diplopia (n=1) and exposure keratopathy (n=1).

Conclusion: Ptosis surgery is a useful adjunct to medical therapy to improve lid height in MG patients with ptosis. Risks of diplopia and exposure keratopathy should be discussed with the patient pre-operatively.

Keywords: External levator advancement; eyelid surgery; myasthenia gravis; ocular myasthenia; ptosis.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Blepharoplasty / methods*
  • Blepharoptosis / etiology
  • Blepharoptosis / surgery*
  • Eyelids / surgery
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myasthenia Gravis / complications*
  • Oculomotor Muscles / surgery
  • Postoperative Complications
  • Retrospective Studies