Herpes Zoster in the Older Adult

Infect Dis Clin North Am. 2017 Dec;31(4):811-826. doi: 10.1016/j.idc.2017.07.016.

Abstract

Herpes zoster (HZ) is the result of reactivation of latent varicella zoster virus (VZV) and occurs most frequently in older adults. Classically, HZ presents as a unilateral, selflimited, dermatomal rash. Postherpetic neuralgia (PHN) is a common sequela, presenting as severe pain that persists after the rash has resolved. In the elderly, PHN can be debilitating and requires a prompt diagnosis, treatment with antivirals, and adequate pain control. A longer-term pain management strategy is required if PHN occurs. A modestly effective vaccine exists and is recommended for older individuals.

Keywords: Older adults; Postherpetic neuralgia; Shingles; Vaccination; Zoster.

Publication types

  • Review

MeSH terms

  • Aged
  • Aging
  • Analgesics / therapeutic use
  • Antiviral Agents / therapeutic use
  • Herpes Zoster / complications
  • Herpes Zoster / drug therapy*
  • Herpes Zoster / pathology*
  • Humans
  • Middle Aged
  • Pain / etiology

Substances

  • Analgesics
  • Antiviral Agents