Retrospective analysis of obstetric and anesthetic management of patients with placenta accreta spectrum disorders

Int J Gynaecol Obstet. 2018 Mar;140(3):370-374. doi: 10.1002/ijgo.12366. Epub 2017 Nov 23.

Abstract

Objective: To assess the management and maternal outcomes of placenta accreta spectrum (PAS) disorders.

Methods: A retrospective chart review was conducted of patients diagnosed with PAS disorders (placenta creta, increta, or percreta) who were treated at a US tertiary care center between February 1, 2011, and January 31, 2016. Obstetric management, anesthetic management, and maternal outcomes were analyzed.

Results: A total of 43 cases were identified; placenta previa was diagnosed among 33 (77%). Median age was 33 years (range 23-42). Median blood loss was 1500 mL (interquartile range 1000-2500); blood loss was greatest among the 10 patients with placenta percreta (3250 mL, interquartile range 2200-6000). Transfusion of blood products was necessary among 14 (33%) patients, with no difference in frequency according to the degree of placental invasion (P=0.107). Surgical complications occurred among 10 (23%) patients. Overall, 30 (70%) patients received combined spinal-epidural plus general anesthesia, 4 (9%) received only general anesthesia, and 9 (21%) underwent surgery with combined spinal-epidural anesthesia. One patient experienced difficult airway and another experienced accidental dural puncture.

Conclusion: Placenta previa and accreta coexist in many patients, leading to substantial bleeding related to the degree of myometrial invasion. An interdisciplinary team approach plus the use of combined spinal-epidural anesthesia, transitioning to general anesthesia, were advisable and safe.

Keywords: High-risk obstetrics; Intrapartum hemorrhage; Obstetric anesthesia; Placenta accreta spectrum disorders; Retrospective study; Uterine bleeding.

MeSH terms

  • Adult
  • Anesthesia, Epidural
  • Anesthesia, General
  • Blood Loss, Surgical / statistics & numerical data
  • Blood Transfusion / statistics & numerical data
  • Cesarean Section*
  • Female
  • Humans
  • Hysterectomy / statistics & numerical data
  • Placenta Accreta / surgery*
  • Placenta Previa / surgery
  • Postoperative Complications
  • Postpartum Hemorrhage / surgery*
  • Pregnancy
  • Retrospective Studies
  • Young Adult