Vitamin D Metabolism in Bariatric Surgery

Endocrinol Metab Clin North Am. 2017 Dec;46(4):947-982. doi: 10.1016/j.ecl.2017.07.006.


Hypovitaminosis D is common in obese patients and persists after roux-en-Y gastric bypass and sleeve gastrectomy. Several societies recommend screening for vitamin D deficiency before bariatric surgery, and replacement doses of 3000 IU/d and up to 50,000 IU 1 to 3 times per week, in case of deficiency, with periodic monitoring. These regimens are mostly based on expert opinion. Large trials are needed to assess the vitamin D dose response, by type of bariatric surgery, and evaluate the effect on surrogate markers of skeletal outcomes. Such data are essential to derive desirable vitamin D levels in this population.

Keywords: Bariatric surgery; Guidelines; Obesity; RYGB; SG; Vitamin D.

Publication types

  • Review

MeSH terms

  • Bariatric Surgery / adverse effects*
  • Humans
  • Postoperative Complications / blood
  • Vitamin D / analogs & derivatives*
  • Vitamin D / blood
  • Vitamin D Deficiency / blood
  • Vitamin D Deficiency / etiology*


  • Vitamin D
  • 25-hydroxyvitamin D