In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan.


Capsaicin is a chili pepper extract, genus Capsicum, with analgesic properties. Since its discovery, it is used as a homeopathic remedy to treat burning pain using the concept of "treating like with like" or counter-irritant. Since the first reports, various preparations of capsaicin are used to treat various chronic painful conditions. Systematic reviews have shown that capsaicin is efficacious in treating a variety of conditions. This activity reviews the mechanism of action, indications, and latest research pertinent for clinicians and other interprofessional team members in the clinical setting.

Publication types

  • Study Guide