Pharmaceutical composition and drug effect of synthetic Bacopa monnieri L. health promoting agent from the perspective of resistance fatigue

Pak J Pharm Sci. 2017 Sep;30(5(Special)):1867-1874.

Abstract

Bacopa monnieri has effect on the nervous system, digestive system and blood circulation systems. In this paper, the authors conducted pharmacological analysis on Bacopa monniera and its innovative pharmaceutical preparation of promote motor function. The extract of the drug has some effect on relieving the fatigue and providing the movement function. By analyzing the composition and efficacy of Chinese herbal extracts, it can be seen that these drugs have obvious effect on improving immunity. Experimental results show that the agent can increase the liver glycogen energy reserves, reduce Bla and BUN levels, balance and energy metabolism of muscle cells in the environment, it plays a positive role to improve the exercise capacity and exercise fatigue.

MeSH terms

  • Amyloid beta-Protein Precursor / genetics
  • Animals
  • Bacopa / chemistry*
  • Blood Urea Nitrogen
  • Body Weight / drug effects
  • Drugs, Chinese Herbal / pharmacology*
  • Fatigue / drug therapy*
  • Gene Expression / drug effects
  • Interleukin-1beta / blood
  • Liver Glycogen / metabolism
  • Malondialdehyde / blood
  • Mice
  • Mice, Transgenic
  • Physical Conditioning, Animal
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use*
  • Proteomics

Substances

  • APP protein, human
  • Amyloid beta-Protein Precursor
  • Drugs, Chinese Herbal
  • Interleukin-1beta
  • Liver Glycogen
  • Plant Extracts
  • Malondialdehyde