Adrenal ganglioneuroma: What you need to know

World J Clin Cases. 2017 Oct 16;5(10):373-377. doi: 10.12998/wjcc.v5.i10.373.


Adrenal ganglioneuromas (GNs) constitute rare, differentiated tumors which originate from neural crest cells. GNs are usually hormonally silent and tend to be discovered incidentally on imaging tests. Adrenalectomy is the gold standard for the treatment of primary adrenal GNs. Nevertheless, preoperative differential diagnosis of GNs remains extremely challenging, and thus histopathological examination is required in order to confirm the diagnosis of GN. Overall, prognosis after surgical resection seems to be excellent, without any recurrences or need for adjuvant therapy.

Keywords: Adrenalectomy; Ganglioneuroma; Neural crest; Neurogenic tumors.

Publication types

  • Review