Analysis of family-wise error rates in statistical parametric mapping using random field theory

Hum Brain Mapp. 2019 May;40(7):2052-2054. doi: 10.1002/hbm.23839. Epub 2017 Nov 1.

Abstract

This technical report revisits the analysis of family-wise error rates in statistical parametric mapping-using random field theory-reported in (Eklund et al. []: arXiv 1511.01863). Contrary to the understandable spin that these sorts of analyses attract, a review of their results suggests that they endorse the use of parametric assumptions-and random field theory-in the analysis of functional neuroimaging data. We briefly rehearse the advantages parametric analyses offer over nonparametric alternatives and then unpack the implications of (Eklund et al. []: arXiv 1511.01863) for parametric procedures. Hum Brain Mapp, 40:2052-2054, 2019. © 2017 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.

Keywords: family-wise error rate; random field theory; statistical parametric mapping; topological inference.

MeSH terms

  • Brain / diagnostic imaging*
  • Brain / physiology
  • Brain Mapping / methods*
  • Brain Mapping / statistics & numerical data
  • Data Interpretation, Statistical*
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Magnetic Resonance Imaging / statistics & numerical data