Newborn Neurons in the Aged Hippocampus-Scarce and Slow but Highly Plastic

Ruth Beckervordersandforth

doi:10.1016/j.celrep.2017.10.049

Newborn Neurons in the Aged Hippocampus-Scarce and Slow but Highly Plastic

Cell Rep. 2017 Oct 31;21(5):1127-1128. doi: 10.1016/j.celrep.2017.10.049.

Author

Ruth Beckervordersandforth¹

Affiliation

¹ Institute of Biochemistry, Emil Fischer Center, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen, Germany. Electronic address: ruth.beckervordersandforth@fau.de.

PMID: 29091752
DOI: 10.1016/j.celrep.2017.10.049

Abstract

In this issue of Cell Reports, Trinchero et al. (2017) demonstrate that newborn neurons in the aged hippocampus are delayed in development but are highly susceptible to stimuli improving neuronal activity. This plasticity is mediated cell-intrinsically by neurotrophin signaling.

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MeSH terms

Hippocampus
Neuronal Plasticity*
Neurons
Plastics*
Temporal Lobe

Substances

Plastics