The authors used computer simulation to investigate the hemodynamics in 36 unruptured aneurysms on the first day the lesions were discovered; 12 of them later ruptured. Knowledge about any differences in hemodynamics at this early stage improves predictions about which patients will get a subarachnoid hemorrhage-a dangerous bleeding in the brain-and helps decide which patients should be treated in advance to avoid the bleeding.
Keywords: ACoA = anterior communicating artery; CFD = computational fluid dynamics; IA = intracranial aneurysm; ICA = internal carotid artery; ICI = inflow concentration index; IQR = interquartile range; LSA = low shear area; MCA = middle cerebral artery; OSI = oscillatory shear index; PCoA = posterior communicating artery; PHASES = population; PLc = pressure loss coefficient; SAH = subarachnoid hemorrhage; VDR = viscous dissipation ratio; WSS = wall shear stress; computational fluid dynamics; hemodynamics; hypertension, age, size of aneurysm, earlier SAH from another aneurysm, site of aneurysm; intracranial aneurysm; rupture; subarachnoid hemorrhage; vascular disorders.