Outcomes of complicated appendicitis: Is conservative management as smooth as it seems?

Am J Surg. 2018 Apr;215(4):586-592. doi: 10.1016/j.amjsurg.2017.10.032. Epub 2017 Nov 1.

Abstract

Background: This study characterized the failure rate of non-operative management (NOM) for complicated appendicitis (CA; perforation, abscess, phlegmon), and compared outcomes among patients undergoing acute appendectomy (AA), elective interval appendectomy (EIA), and unplanned appendectomy after failing to improve with NOM.

Methods: Adults treated at one facility between 2007 and 2014 were retrospectively studied.

Results: Ninety-five patients presented with CA. Sixty individuals underwent AA. The remaining 35 patients initially underwent NOM: 14 underwent EIA, nine (25.7%) failed NOM, 12 never underwent surgery. All patients failing NOM had an open operation with most (55.6%) requiring bowel resection. AA and EIA were comparable in surgical approach, bowel resection and post-operative readmission. However, AA demonstrated a lower incidence of bowel resection (3.3% vs 17.1%, P = 0.048) when compared to all patients initially undergoing NOM.

Conclusions: Due to the high incidence of failed NOM and the morbidity associated with failure, AA may be appropriate for CA.

Keywords: Complicated appendicitis; Interval appendectomy; Perforated appendicitis.

MeSH terms

  • Appendectomy / statistics & numerical data
  • Appendicitis / complications*
  • Appendicitis / surgery
  • Appendicitis / therapy*
  • Conservative Treatment / methods*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Treatment Failure
  • Treatment Outcome