Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2018 Dec;38(6):2335-2339.
doi: 10.1007/s10792-017-0731-z. Epub 2017 Nov 4.

Thermal Imaging of Corneal Transplant Rejection

Case Reports

Thermal Imaging of Corneal Transplant Rejection

Matthew C Sniegowski et al. Int Ophthalmol. .


Purpose: Corneal transplant rejection is one of the most frequent complications, with a reported incidence of 16-30%. In our current research, we investigated the use of infrared thermography to detect ocular surface temperature. We also looked at a case of corneal transplant rejection and this case had an elevated ocular surface temperature when compared to the contralateral eye and other eyes without corneal transplant rejection.

Methods: Twenty-three eyes of twelve patients would serve as control to one eye with clinically evident corneal transplant graft rejection. A Flir T400 320 × 240 pixel, digital thermal camera was used to take a digital photograph and an infrared photograph of each eye. The images were analyzed with the Flir web viewer.

Results: We present here a case of corneal transplant rejection documented with both slit lamp photos as well as infrared and corneal surface photos. The studied patient's unaffected eye, and the control group's trends did indeed bring the expected results and proved thermal imagery in this particular field a viable examination method.

Conclusions: We feel that ocular thermography is a useful adjunctive diagnostic tool and that it may be useful to monitor routine corneal transplant patients. Further research into the temperature changes of corneal transplant patients is needed and may allow for earlier intervention for graft rejection.

Keywords: Corneal transplant; Graft rejection; Infrared thermography; Penetrating keratoplasty.

Similar articles

See all similar articles

Cited by 2 articles


    1. Br J Ophthalmol. 1968 Oct;52(10):729-41 - PubMed
    1. Int Ophthalmol. 2008 Dec;28(6):399-405 - PubMed
    1. Optom Vis Sci. 1990 Dec;67(12):886-90 - PubMed
    1. Am J Ophthalmol. 2011 Sep;152(3):358-363.e2 - PubMed
    1. Br J Ophthalmol. 2007 Jul;91(7):878-81 - PubMed

Publication types

LinkOut - more resources