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, 10 (3), 261-266

Effect of Casein Phosphopeptide-amorphous Calcium Phosphate and Calcium Sodium Phosphosilicate on Artificial Carious Lesions: An in vitro Study

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Effect of Casein Phosphopeptide-amorphous Calcium Phosphate and Calcium Sodium Phosphosilicate on Artificial Carious Lesions: An in vitro Study

Iqra Chaudhary et al. Int J Clin Pediatr Dent.

Abstract

Aim: To compare new remineralizing agents calcium sodium phosphosilicate paste and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) paste with that of fluoridated toothpaste in remineralization of early carious lesions using scanning electron microscopy and energy-dispersive X-ray (SEM-EDX) analysis.

Materials and methods: Sixty sound extracted premolars were collected and placed in demineralizing solution for 4 days to produce artificial carious lesions. All specimens were evaluated for any loss of mineral content using SEM-EDX analysis. Samples were randomly assigned to three groups: Group I: Fluoridated toothpaste (control), group II: CPP-ACP paste, and group III: Calcium sodium phosphosilicate paste. Specimens were then treated with above-mentioned remineralizing agents and again measured for mineral content using SEM-EDX analysis.

Results: Group III (calcium sodium phosphosilicate paste) showed highest significant difference followed in descending order by group II (CPP-ACP paste) and group I (fluoridated toothpaste).

Conclusion: Calcium sodium phosphosilicate paste showed maximum remineralizing potential compared with CPP-ACP and fluoridated toothpastes.

How to cite this article: Chaudhary I, Tripathi AM, Yadav G, Saha S. Effect of Casein Phosphopeptide-amorphous Calcium Phosphate and Calcium Sodium Phosphosilicate on Artificial Carious Lesions: An in vitro Study. Int J Clin Pediatr Dent 2017;10(3):261-266.

Keywords: Calcium sodium phosphosilicate; Casein phos-phopeptide-amorphous calcium phosphate; Demineralization; Fluoride; Remineralization; Scanning electron microscopy and energy-dispersive X-ray analysis.

Conflict of interest statement

Source of support: Nil Conflict of interest: None

Figures

Fig. 1:
Fig. 1:
Structural analysis of demineralized enamel sample by SEM
Fig. 2:
Fig. 2:
Structural analysis of remineralized enamel sample treated with fluoridated toothpaste by SEM
Graph 1:
Graph 1:
Elemental analysis of demineralized enamel sample by SEM-EDX analysis
Graph 2:
Graph 2:
Elemental analysis of remineralized enamel sample treated with fluoridated toothpaste by SEM-EDX analysis
Fig. 3:
Fig. 3:
Structural analysis of remineralized enamel sample treated with CPP-ACP paste by SEM
Fig. 4:
Fig. 4:
Structural analysis of remineralized enamel sample treated with calcium sodium phosphosilicate paste by SEM
Graph 3:
Graph 3:
Elemental analysis of remineralized enamel sample treated with CPP-ACP paste by SEM-EDX analysis
Graph 4:
Graph 4:
Elemental analysis of remineralized enamel sample treated with calcium sodium phosphosilicate paste by SEM-EDX analysis
Graph 5:
Graph 5:
Change in calcium and phosphorous concentrations between demineralization and remineralization cycles in the three study groups. SD: Standard deviation
Graph 6:
Graph 6:
Change in Ca/P ratios between demineralization and remineralization cycles in the three study groups. SD: Standard deviation

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