Chronic kidney disease: Intensive blood pressure reduction lowers mortality in CKD

Stephen P Juraschek; Lawrence J Appel

doi:10.1038/nrneph.2017.154

Chronic kidney disease: Intensive blood pressure reduction lowers mortality in CKD

Nat Rev Nephrol. 2018 Jan;14(1):5-6. doi: 10.1038/nrneph.2017.154. Epub 2017 Nov 7.

Authors

Stephen P Juraschek¹, Lawrence J Appel²

Affiliations

¹ Johns Hopkins University School of Medicine, The Johns Hopkins Bloomberg School of Public Health, Maryland 21205, USA; The Welch Center for Prevention, Epidemiology and Clinical Research, 2024 East Monument Street, Baltimore, Maryland 21205, USA; and at the Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, Massachusetts 02215, USA.
² Johns Hopkins University School of Medicine, The Johns Hopkins Bloomberg School of Public Health, Maryland 21205, USA; and The Welch Center for Prevention, Epidemiology and Clinical Research, 2024 East Monument Street, Baltimore, Maryland 21205, USA.

Abstract

Hypertension is a risk factor for chronic kidney disease (CKD), but the optimal blood pressure (BP) target in patients with stage 3–5 CKD is unclear. Now, a meta-analysis reports that more-intensive BP control is associated with a reduced risk of all-cause mortality compared with less-intensive BP goals in this high-risk population.

Publication types

Comment

MeSH terms

Antihypertensive Agents
Blood Pressure / drug effects
Blood Pressure Determination
Humans
Renal Insufficiency, Chronic*

Substances

Antihypertensive Agents

Abstract

Publication types

MeSH terms

Substances

Grants and funding