Extensively drug resistant tuberculosis in Mali: a case report

BMC Res Notes. 2017 Nov 6;10(1):561. doi: 10.1186/s13104-017-2890-4.


Background: Drug resistant tuberculosis presents a major public health challenge.

Case presentation: We present here the first two patients diagnosed with extensively drug resistant tuberculosis in Bamako, Mali. Genotypic findings suggest possible nosocomial transmission from the first patient to the second one, resulting in superinfection of the second patient. After being diagnosed with extensively drug resistant tuberculosis in August 2016, the patients only started receiving appropriate treatment 10 months later.

Conclusion: The identification of these patients highlights the need for improved diagnostic and treatment algorithms for better surveillance and management of drug resistance in Mali. In the interest of these as well as future patients suffering from resistant tuberculosis, all steps recommended for programmatic management of drug resistant tuberculosis must be urgently prioritized in order to strengthen the multidrug resistant tuberculosis program.

Keywords: Bamako; Mali; Treatment; XDR-TB.

MeSH terms

  • Adult
  • Extensively Drug-Resistant Tuberculosis / diagnosis
  • Extensively Drug-Resistant Tuberculosis / drug therapy
  • Extensively Drug-Resistant Tuberculosis / epidemiology*
  • Extensively Drug-Resistant Tuberculosis / microbiology
  • Female
  • Humans
  • Mali / epidemiology
  • Microbial Sensitivity Tests
  • Middle Aged
  • Mycobacterium tuberculosis / physiology