Postoperative management of heart transplantation patients

Best Pract Res Clin Anaesthesiol. 2017 Jun;31(2):201-213. doi: 10.1016/j.bpa.2017.06.002. Epub 2017 Jun 23.

Abstract

Heart transplant recipients are at risk for a number of post-transplantation complications such as graft dysfunction, rejection, and infection. The rates of many complications are decreasing over time, and prognosis is improving. However, these patients continue to experience significant morbidity and mortality. This review focuses on the optimal management of heart transplant recipients in the postoperative period, based on current knowledge. More information is needed about the best ways to predict, prevent, and treat primary graft dysfunction, right ventricular failure, and cellular and antibody-mediated rejection.

Keywords: acute cellular rejection; antibody-mediated rejection; heart transplantation; immunosuppression; primary graft dysfunction; right ventricular failure.

Publication types

  • Review

MeSH terms

  • Graft Rejection / etiology
  • Graft Rejection / physiopathology
  • Graft Rejection / prevention & control
  • Heart Failure / diagnosis
  • Heart Failure / physiopathology
  • Heart Failure / surgery*
  • Heart Transplantation / adverse effects
  • Heart Transplantation / trends*
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Postoperative Care / methods*
  • Postoperative Care / trends
  • Postoperative Complications / etiology
  • Postoperative Complications / physiopathology
  • Postoperative Complications / prevention & control*

Substances

  • Immunosuppressive Agents