Chromosome Segregation: Is the Spindle All About Microtubules?

Curr Biol. 2017 Nov 6;27(21):R1168-R1170. doi: 10.1016/j.cub.2017.09.022.

Abstract

The spindle segregates chromosomes in cell division and it has long been discussed whether it is microtubules alone that build this fundamental molecular machine. Recent work in mouse oocytes now shows that actin filaments co-assemble with microtubules to promote faithful chromosome segregation.

Publication types

  • Comment

MeSH terms

  • Actins / genetics*
  • Animals
  • Chromosome Segregation*
  • Chromosomes
  • Mice
  • Microtubules
  • Oocytes
  • Spindle Apparatus

Substances

  • Actins