Abstract
A gradient in concentration of the protein product of the bicoid gene is a determinant of the anterior-posterior axis of Drosophila embryos. By binding upstream of the segmentation gene hunchback the bicoid protein controls its transcription, thereby translating maternal pattern-generating information into differential activation of zygotic gene expression.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Base Sequence
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Drosophila / embryology
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Drosophila / genetics*
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Drosophila Proteins
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Embryo, Nonmammalian / physiology
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Genes
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Genes, Regulator*
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Homeodomain Proteins*
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Insect Hormones / genetics*
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Insect Hormones / physiology
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Molecular Sequence Data
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Restriction Mapping
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Trans-Activators*
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Transcription, Genetic*
Substances
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Drosophila Proteins
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Homeodomain Proteins
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Insect Hormones
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Trans-Activators
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bcd protein, Drosophila