Deep vein thrombosis in pediatric patients

Pediatr Blood Cancer. 2018 Mar;65(3). doi: 10.1002/pbc.26881. Epub 2017 Nov 8.

Abstract

Due to advances in caring for critically ill children and those with chronic diseases, rates of deep vein thrombosis (DVT) are increasing in children. Risk factors consist of central venous catheters, chronic medical conditions, thrombophilia, and various medications. Compression Doppler ultrasonography is the method most commonly used to diagnose DVT, and patients will usually present with pain and swelling of the affected limb. Anticoagulation via subcutaneous injection is the most common treatment regime for children with DVT, and the new, direct oral anticoagulants are currently under investigation. Prevention techniques are not established, but clinical studies are addressing this need.

Keywords: anticoagulation therapy; coagulation thrombolytic; hematology hemostasis and thrombosis; thrombophilia; thrombosis; thrombotic disorders.

Publication types

  • Review

MeSH terms

  • Anticoagulants / therapeutic use
  • Child
  • Female
  • Humans
  • Male
  • Risk Factors
  • Thrombolytic Therapy / methods
  • Venous Thrombosis / diagnosis*
  • Venous Thrombosis / etiology*
  • Venous Thrombosis / therapy*

Substances

  • Anticoagulants