[The pentoxifylline, a corticosteroid sparing in the treatment of sarcoidosis: A case report]

Abstract

Introduction: The pentoxifylline seems to have some effects on immune cells by inhibiting tumor necrosis factor alpha (TNFα). Its role as a sparing corticosteroids in the treatment of sarcoidosis remains to be defined.

Clinical case: We present the case of a patient with sarcoidosis corticodependent despite the use of azathioprine. It was finally improved clinically, functionally and by a thoracic computed tomography with addition of pentoxifylline.

Conclusion: When the tolerance of the pentoxifylline is good and there is not a bleeding risk, the benefit-risk in the long term might be interesting in some patients with sarcoidosis corticodependent.

Keywords: Sarcoidose; Sarcoidosis; Steroid sparing; Épargneur de corticoïdes.