Citrobacter freundii produces an 18-amino-acid heat-stable enterotoxin identical to the 18-amino-acid Escherichia coli heat-stable enterotoxin (ST Ia)

Infect Immun. 1989 Feb;57(2):649-52. doi: 10.1128/iai.57.2.649-652.1989.

Abstract

We purified and sequenced the heat-stable enterotoxin produced by Citrobacter freundii. The toxin was detected during purification by reaction with monoclonal antibody to Escherichia coli heat-stable enterotoxin. The C. freundii toxin amino acid sequence was identical to that of the 18-amino-acid heat-stable enterotoxin (STa) produced by toxigenic E. coli.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Amino Acids / isolation & purification*
  • Bacterial Toxins / biosynthesis*
  • Bacterial Toxins / isolation & purification
  • Citrobacter / analysis
  • Citrobacter / metabolism*
  • Enterotoxins / biosynthesis*
  • Enterotoxins / isolation & purification
  • Escherichia coli Proteins
  • Molecular Sequence Data
  • Sequence Homology, Nucleic Acid

Substances

  • Amino Acids
  • Bacterial Toxins
  • Enterotoxins
  • Escherichia coli Proteins
  • heat stable toxin (E coli)