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Case Reports
. 2018 Feb;24(2):381-383.
doi: 10.3201/eid2402.171756. Epub 2018 Feb 17.

Ceftriaxone-Resistant Neisseria gonorrhoeae, Canada, 2017

Brigitte Lefebvre, Irene Martin, Walter Demczuk, Lucie Deshaies, Stéphanie Michaud, Annie-Claude Labbé, Marie-Claude Beaudoin, Jean Longtin
Case Reports

Ceftriaxone-Resistant Neisseria gonorrhoeae, Canada, 2017

Brigitte Lefebvre et al. Emerg Infect Dis. 2018 Feb.

Abstract

We identified a ceftriaxone-resistant Neisseria gonorrhoeae isolate in a patient in Canada. This isolate carried the penA-60 allele, which differs substantially from its closest relative, mosaic penA XXVII (80% nucleotide identity). Epidemiologic and genomic data suggest spread from Asia. Antimicrobial susceptibility surveillance helps prevent spread of highly resistant N. gonorrhoeae strains.

Keywords: Canada; Neisseria gonorrhoeae; North America; antimicrobial resistance; antimicrobial susceptibility surveillance; bacteria; ceftriaxone; ceftriaxone-resistant; gonorrhea; mosaic penA allele; penA-60; sexually transmitted infections.

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