Ceftriaxone-Resistant Neisseria gonorrhoeae, Canada, 2017

Emerg Infect Dis. 2018 Feb;24(2):381-383. doi: 10.3201/eid2402.171756. Epub 2018 Feb 17.


We identified a ceftriaxone-resistant Neisseria gonorrhoeae isolate in a patient in Canada. This isolate carried the penA-60 allele, which differs substantially from its closest relative, mosaic penA XXVII (80% nucleotide identity). Epidemiologic and genomic data suggest spread from Asia. Antimicrobial susceptibility surveillance helps prevent spread of highly resistant N. gonorrhoeae strains.

Keywords: Canada; Neisseria gonorrhoeae; North America; antimicrobial resistance; antimicrobial susceptibility surveillance; bacteria; ceftriaxone; ceftriaxone-resistant; gonorrhea; mosaic penA allele; penA-60; sexually transmitted infections.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Asia
  • Canada / epidemiology
  • Ceftriaxone / pharmacology*
  • Drug Resistance, Bacterial
  • Female
  • Gonorrhea / drug therapy
  • Gonorrhea / epidemiology
  • Gonorrhea / microbiology*
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Neisseria gonorrhoeae / drug effects*
  • Neisseria gonorrhoeae / genetics
  • Travel
  • Young Adult


  • Anti-Bacterial Agents
  • Ceftriaxone