Neuropsychiatric Factors Linked to Adherence and Short-Term Outcome in a U.S. Functional Neurological Disorders Clinic: A Retrospective Cohort Study

J Neuropsychiatry Clin Neurosci. Spring 2018;30(2):152-159. doi: 10.1176/appi.neuropsych.17060117. Epub 2017 Nov 14.


Despite advancements in the assessment and management of functional neurological disorder (FND), the feasibility of implementing a new standard of care remains unclear. Chart reviews were performed for 100 patients with motor FND to investigate factors related to treatment adherence and clinical improvement over an average follow-up of 7 months. Of 81 patients who returned for follow-up, a history of chronic pain disorder inversely correlated with improvement. Of the 50 individuals newly referred for treatment, adherence correlated with improvement, while having abnormal neuroimaging inversely correlated with improvement. This study supports the feasibility of applying a new standard of care for FND.

Keywords: Behavioral Therapy (Neuropsychiatric Aspects); Somatoform Disorders.

MeSH terms

  • Chronic Pain / psychology
  • Cohort Studies
  • Comorbidity
  • Follow-Up Studies
  • Humans
  • Motor Disorders / diagnosis
  • Motor Disorders / therapy*
  • Nervous System Diseases / diagnosis
  • Nervous System Diseases / therapy
  • Neuropsychiatry
  • Prognosis
  • Psychology, Social
  • Retrospective Studies
  • Standard of Care*
  • Symptom Assessment
  • Treatment Adherence and Compliance*
  • Treatment Outcome