Ventilator Strategies for Chronic Obstructive Pulmonary Disease and Acute Respiratory Distress Syndrome

Surg Clin North Am. 2017 Dec;97(6):1381-1397. doi: 10.1016/j.suc.2017.07.006.


The management of the ventilator in patients with chronic obstructive pulmonary disease (COPD) and acute respiratory distress syndrome (ARDS) has a dramatic effect on the overall outcome. The incidence of COPD is increasing as the US population grows older. The most effective means to deal with pulmonary complications is to avoid them, but both COPD and ARDS have evidence-based interventions that have been shown to improve outcomes. Pulmonary complications affect up to 40% of patients, and their occurrence is associated with an increased duration of hospital stay, and an increased mortality.

Keywords: ALI; APRV; ARDS; Airway pressure release ventilation; COPD; Hypoxia; PEEP; Respiratory failure.

Publication types

  • Review

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Helium / therapeutic use
  • Humans
  • Oxygen / therapeutic use
  • Positive-Pressure Respiration, Intrinsic / diagnosis
  • Positive-Pressure Respiration, Intrinsic / therapy
  • Pulmonary Disease, Chronic Obstructive / physiopathology
  • Pulmonary Disease, Chronic Obstructive / therapy*
  • Pulmonary Gas Exchange / physiology
  • Respiration, Artificial / methods*
  • Respiratory Distress Syndrome / physiopathology
  • Respiratory Distress Syndrome / therapy*
  • Respiratory Muscles / physiology
  • Risk Factors
  • Treatment Outcome
  • Ventilator Weaning / methods


  • Adrenal Cortex Hormones
  • Helium
  • heliox
  • Oxygen