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. 2017 Nov 13;7(1):15414.
doi: 10.1038/s41598-017-15770-2.

Coupling of Oxy- and Deoxyhemoglobin concentrations with EEG rhythms during motor task

Piotr Lachert  1 , Dariusz Janusek  2 , Przemyslaw Pulawski  2 , Adam Liebert  2 , Daniel Milej  2 , Katarzyna J Blinowska  2   3
Affiliations

Coupling of Oxy- and Deoxyhemoglobin concentrations with EEG rhythms during motor task

Piotr Lachert et al. Sci Rep. .

Abstract

A relationship between the brain rhythmic activity and the hemodynamic response was studied using the simultaneous measurement of electroencephalogram (EEG) and the functional near-infrared spectroscopy (fNIRS) during a motor task (self-paced right finger movements) for 10 subjects. An EEG recording with a 32-electrode (10-10) system was made and the hemodynamic response was obtained using 8 optodes placed over the sensorimotor cortex on both hemispheres. During the task an increase in oxyhemoglobine (HbO) was accompanied by a decrease in deoxyhemoglobine (HbR) concentration and a decrease in amplitudes (desynchronisation) of alpha (8-13 Hz) and beta (13-30 Hz) EEG rhythms. These phenomena were prominent in the hemisphere contralateral to the moving finger. The delays between the hemodynamic and electrophysiological variables were on average 2.8 s. Highly significant (p < 0.0001) negative Pearson correlations were found between HbO and alpha (r2 = -0.69) and HbO and beta (r2 = -0.54) rhythms. Positive correlations r2 = 0.5 between these rhythms and HbR were found.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Figure 1
Figure 1
ERD/ERS distributions (left panels) and concentration changes in time for HbO (red) and HbR (blue) - (right panels) averaged over subjects. Upper pictures correspond to the most reactive electrode - C3 and corresponding optode; lower pictures to the electrode located in the right hemisphere - Cp2 and corresponding optode. Movement period from 0 to 20 s. At the very left of ERD/ERS panels - spectra.
Figure 2
Figure 2
Topographic distribution of desynchronisation in alpha and beta bands (upper pictures) and a decrease in HbR and an increase in HbO (lower pictures) quantified by their z-scores. Blue colors illustrate a decrease whereas red and yellow colors represent an increase.
Figure 3
Figure 3
The time evolutions of HbO concentration (red), HbR concentration (blue) (upper picture), alpha ERD/ERS (black), beta ERD/ERS (green) (lower picture) for the most reactive electrode (C3) and the corresponding optode averaged over subjects. Movement period from 0 to 20 s.
Figure 4
Figure 4
Time scheme of the protocol with indication of no movement period (REST) and movement period (MOV).
Figure 5
Figure 5
Location pattern of EEG electrodes and NIRS optodes.
See this image and copyright information in PMC

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