Renal Dysfunction Following Elective Endovascular Aortic Aneurysm Repair

Curr Vasc Pharmacol. 2019;17(2):133-140. doi: 10.2174/1570161115666171116163203.

Abstract

Abdominal aortic aneurysm (AAA) is a degenerative disease of the aortic wall with potentially fatal complications. Open repair (OR) was considered the gold standard, until the emergence of endovascular aneurysm repair (EVAR), which is less invasive and equally (if not more) effective. As the popularity of endovascular procedures grows, related complications become more evident, with kidney damage being one of them. Although acute kidney injury (AKI) following EVAR is relatively common, its true incidence is still uncertain. Also, there is insufficient data concerning long-term renal outcomes after EVAR, especially with repeated contrast agent exposure. Despite the lack of firm evidence on the effectiveness of individual strategies, it is evident that prevention of AKI following EVAR requires a multifactorial approach. This review focuses on recent findings based on human studies regarding the current evidence of renal impairment after EVAR, its quantification and strategies for its prevention.

Keywords: EVAR; Endovascular aneurysm repair; OR; Scr; acute kidney injury; contrast-induced nephropathy..

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Acute Kidney Injury / diagnosis
  • Acute Kidney Injury / epidemiology
  • Acute Kidney Injury / physiopathology
  • Acute Kidney Injury / prevention & control*
  • Aortic Aneurysm, Abdominal / diagnostic imaging
  • Aortic Aneurysm, Abdominal / surgery*
  • Blood Vessel Prosthesis Implantation / adverse effects*
  • Elective Surgical Procedures / adverse effects
  • Endovascular Procedures / adverse effects*
  • Glomerular Filtration Rate
  • Humans
  • Kidney / physiopathology*
  • Protective Factors
  • Risk Assessment
  • Risk Factors
  • Time Factors
  • Treatment Outcome