Gastrointestinal and Hepatic Disease in Sjogren Syndrome

Yevgeniy Popov; Karen Salomon-Escoto

doi:10.1016/j.rdc.2017.09.010

Gastrointestinal and Hepatic Disease in Sjogren Syndrome

Rheum Dis Clin North Am. 2018 Feb;44(1):143-151. doi: 10.1016/j.rdc.2017.09.010.

Authors

Yevgeniy Popov¹, Karen Salomon-Escoto²

Affiliations

¹ Department of Medicine, University of Massachusetts Medical School, 119 Belmont Street, Worcester, MA 01605, USA. Electronic address: yevgeniy.popov@umassmemorial.org.
² Rheumatology Division, University of Massachusetts Medical School, 119 Belmont Street, Worcester, MA 01605, USA.

PMID: 29149922
DOI: 10.1016/j.rdc.2017.09.010

Abstract

Sjogren syndrome (SS) is a lymphocyte-mediated, infiltrative autoimmune disorder characterized by destruction of exocrine glands leading to secretory dysfunction. The typical manifestations include xerostomia and xerophthalmia; however, extensive gastrointestinal involvement is increasingly being recognized, emphasizing the variable and systemic nature of SS.

Keywords: Dysphagia; Hepatitis; Oral involvement; Pancreatitis; Sicca; Sjogren syndrome; Xerostomia.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Autoimmunity / immunology
Gastrointestinal Diseases* / diagnosis
Gastrointestinal Diseases* / etiology
Gastrointestinal Diseases* / immunology
Gastrointestinal Tract / immunology
Gastrointestinal Tract / physiopathology
Humans
Sjogren's Syndrome* / immunology
Sjogren's Syndrome* / physiopathology