Peripheral Arterial Disease

Heart Lung Circ. 2018 Apr;27(4):427-432. doi: 10.1016/j.hlc.2017.10.014. Epub 2017 Nov 7.


Peripheral arterial disease (PAD) affects 15% of the Australian population and is a powerful and serious predictor of cardiovascular mortality yet continues to be under-recognised and undertreated. Diagnosis is simple and management is centred upon symptom relief and risk minimisation. While novel and specialised therapies play a role, the bulk of management is approachable and feasible. In this review, we cover the epidemiology, risk factors, associated conditions, classification, and natural history of PAD. We then discuss current diagnostic and therapeutic options as well as emerging therapies for this common condition.

Keywords: Cardiovascular disease; Peripheral arterial disease; Peripheral vascular disease; Review.

Publication types

  • Review

MeSH terms

  • Disease Management*
  • Global Health
  • Humans
  • Morbidity / trends
  • Peripheral Arterial Disease* / diagnosis
  • Peripheral Arterial Disease* / epidemiology
  • Peripheral Arterial Disease* / therapy
  • Risk Assessment*
  • Risk Factors
  • Survival Rate / trends