Emergence of sequence type 252 Enterobacter cloacae producing GES-5 carbapenemase in a Czech hospital

Diagn Microbiol Infect Dis. 2018 Feb;90(2):148-150. doi: 10.1016/j.diagmicrobio.2017.10.011. Epub 2017 Oct 19.

Abstract

ST252 Enterobacter cloacae, producing GES-5 carbapenemase, was isolated in a Czech hospital. blaGES-5 was part of a novel class 1 integron, In1406, which also included a new allele of the aadA15 gene cassette. In1406 was located on a ColE2-like plasmid, pEcl-35771cz (6953bp).

Keywords: Class 1 integron; Class A β-lactamase; ColE2-like; Enterobacteriaceae; In1406.

MeSH terms

  • Bacterial Proteins / genetics*
  • Czech Republic
  • Enterobacter cloacae / enzymology
  • Enterobacter cloacae / genetics*
  • Enterobacteriaceae Infections / microbiology*
  • Hospitals
  • Humans
  • Integrons / genetics
  • Multilocus Sequence Typing
  • beta-Lactamases / genetics*

Substances

  • Bacterial Proteins
  • beta-Lactamases
  • carbapenemase