Microbial transformation of resveratrol by endophyte Streptomyces sp. A12 isolated from Polygonum cuspidatum

Tian Jiewei; Wang Lei; Long Xiufeng; Zhang Heming; Li Xiaoguang; Fu Haiyan; Tian Yongqiang

doi:10.1080/14786419.2017.1405411

Microbial transformation of resveratrol by endophyte Streptomyces sp. A12 isolated from Polygonum cuspidatum

Nat Prod Res. 2018 Oct;32(19):2343-2346. doi: 10.1080/14786419.2017.1405411. Epub 2017 Nov 20.

Authors

Tian Jiewei¹, Wang Lei¹, Long Xiufeng¹, Zhang Heming¹, Li Xiaoguang¹, Fu Haiyan², Tian Yongqiang¹

Affiliations

¹ a Key Laboratory of Leather Chemistry and Engineering (Sichuan University), Ministry of Education and College of Light Industry, Textile & Food Engineering , Sichuan University , Chengdu , China.
² b College of Chemistry , Sichuan University , Chengdu , China.

PMID: 29156986
DOI: 10.1080/14786419.2017.1405411

Abstract

Resveratrol (1) undergoes microbial transformation when fermented with Streptomyces sp. A12 to yield 3, 5, 4'-trimethoxy-trans-stilbene (2). The structure of the compound 2 was elucidated using the modern spectroscopic techniques. This is the first report of the microbial transformation of resveratrol to compound 2 using the endophyte isolated from Polygonum cuspidatum.

Keywords: Microbial transformation; Polygonum cuspidatum; Streptomyces sp.; endophyte.

MeSH terms

Endophytes / metabolism
Molecular Structure
Polygonum / microbiology*
Resveratrol
Spectrum Analysis
Stilbenes / metabolism*
Streptomyces / metabolism*
Transformation, Bacterial*

Substances

Stilbenes
Resveratrol