Role of Endoscopic Ultrasound in the Management of Tubercular Uveitis

Ocul Immunol Inflamm. 2018;26(7):1107-1114. doi: 10.1080/09273948.2017.1322615. Epub 2017 Nov 20.


Purpose: To evaluate the role and safety of endoscopic ultrasound-guided fine-needle aspiration cytology (EUS-FNAC) in patients of tubercular uveitis.

Design: Interventional case series Methods: Thirty patients suspected of tubercular uveitis that underwent EUS-FNAC were enrolled in the study. The patient details recorded were age, gender, systemic history, ocular complaints and clinical manifestations. The details of the investigations - skin test, X-Ray chest, CECT (contrast enhanced computed tomography) of chest and findings on EUS-FNAC were also recorded.

Results: Thirty patients with suspected tubercular uveitis showed mediastinal lymphadenopathy on CECT-chest and underwent EUS-FNAC. A total of 27 patients showed tubercular lymphadenitis and three patients showed reactive lymphadenopathy. Ziehl-Neelsen (ZN) staining was positive for acid-fast bacilli in four cases and culture was positive in one case. There were no noted complications of EUS-FNAC.

Conclusion: EUS-FNAC is a safe and efficacious procedure for confirming the diagnosis of tubercular uveitis and should be routinely employed wherever available.

Keywords: Endoscopic ultrasound; FNAC; mediastinal lymphadenopathy; tuberculosis; uveitis.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy, Fine-Needle
  • Endosonography*
  • Female
  • Humans
  • Lymphadenopathy / diagnostic imaging*
  • Male
  • Mediastinal Diseases / diagnostic imaging*
  • Middle Aged
  • Prospective Studies
  • Radiography, Thoracic
  • Skin Tests
  • Tomography, X-Ray Computed
  • Tuberculosis, Ocular / diagnostic imaging*
  • Tuberculosis, Pulmonary / diagnosis
  • Uveitis / diagnostic imaging*
  • Young Adult