Ethnic Considerations and Multiple Sclerosis Disease Variability in the United States

Neurol Clin. 2018 Feb;36(1):151-162. doi: 10.1016/j.ncl.2017.08.007.


Minorities in the United States such as African Americans and Hispanics may have more severe disease than non-Hispanic whites. Factors contributing to these disparities are reviewed. The variations in disability from non-Hispanic whites may be the result of differences in clinical presentation, genetic underpinnings, and sociocultural factors. Creating awareness and increasing participation in research studies may improve our understanding.

Keywords: African American; Ethnicity; Genetic admixture; Health disparity; Hispanic; Race.

Publication types

  • Review

MeSH terms

  • African Americans
  • European Continental Ancestry Group
  • Female
  • Health Status Disparities*
  • Hispanic Americans
  • Humans
  • Male
  • Multiple Sclerosis / ethnology*
  • United States