Perfusion Imaging in Acute Traumatic Brain Injury

Neuroimaging Clin N Am. 2018 Feb;28(1):55-65. doi: 10.1016/j.nic.2017.09.002. Epub 2017 Oct 23.


Traumatic brain injury (TBI) is a significant problem worldwide and neuroimaging plays a critical role in diagnosis and management. Recently, perfusion neuroimaging techniques have been explored in TBI to determine and characterize potential perfusion neuroimaging biomarkers to aid in diagnosis, treatment, and prognosis. In this article, computed tomography (CT) bolus perfusion, MR imaging bolus perfusion, MR imaging arterial spin labeling perfusion, and xenon CT are reviewed with a focus on their applications in acute TBI. Future research directions are also discussed.

Keywords: Concussion; Perfusion; TBI; Traumatic brain injury.

Publication types

  • Review

MeSH terms

  • Brain / diagnostic imaging
  • Brain Injuries / diagnostic imaging*
  • Diagnostic Imaging / methods*
  • Humans
  • Neuroimaging / methods
  • Perfusion Imaging / methods*