Post-traumatic knee MRI findings and associations with patient, trauma, and clinical characteristics: a subgroup analysis in primary care in the Netherlands

Br J Gen Pract. 2017 Dec;67(665):e851-e858. doi: 10.3399/bjgp17X693653.

Abstract

Background: The added value of magnetic resonance imaging (MRI) in primary care is still being debated. A high diagnostic yield can be expected in young and active patients with post-traumatic knee complaints.

Aim: To determine the frequency of MRI abnormalities in young and active patients (aged 18-45 years) and the associations with patient, trauma, and clinical characteristics.

Design and setting: A subgroup analysis of 174 patients, aged 18-45 years with knee trauma of <6 months, allocated to MRI in a randomised controlled trial on the yield of MRI in primary care. Patients were recruited by 150 GPs in the Netherlands from October 2012 to November 2015.

Method: Associations were expressed using mean differences, odds ratio (OR) and predictive values.

Results: Sixty-seven out of 174 patients (39%) had a positive MRI finding, predominantly anterior cruciate ligament (ACL) ruptures (22%) and/or traumatic meniscal tears (15%). Patients with a pre-existing musculoskeletal comorbidity had a two-fold lower prevalence of positive MRI findings (21%), OR 3.0 (95% confidence interval [CI] = 1.3 to 7.0). A 'sports related trauma' showed the highest OR of 4.6 (95% CI = 2.2 to 9.3) for a positive MRI finding. Clinical scores were statistically, significantly worse in patients with positive MRI findings, with mean differences ranging from 10 to 20%. Furthermore, increasing duration of complaints was correlated with decreasing prevalence rates of positive MRI findings. Overall, a popping sound and direct swelling showed the highest positive predictive value of 65% for the presence of positive MRI findings.

Conclusion: The results from this study enable a preselection of patients to increase the diagnostic yield of MRI in primary care.

Keywords: anterior cruciate ligament injuries; early diagnosis; knee injuries; magnetic resonance imaging; tibial meniscus injuries.

MeSH terms

  • Adult
  • Anterior Cruciate Ligament Injuries / diagnostic imaging*
  • Anterior Cruciate Ligament Injuries / pathology
  • Cartilage, Articular / pathology
  • Comorbidity
  • Contusions / pathology*
  • Female
  • Humans
  • Knee Injuries / diagnostic imaging*
  • Knee Injuries / pathology
  • Magnetic Resonance Imaging*
  • Male
  • Netherlands
  • Practice Patterns, Physicians'
  • Predictive Value of Tests
  • Prevalence
  • Primary Health Care*
  • Referral and Consultation
  • Sensitivity and Specificity
  • Synovitis / diagnostic imaging*
  • Synovitis / pathology
  • Tibial Meniscus Injuries / diagnostic imaging*
  • Tibial Meniscus Injuries / pathology
  • Young Adult