We describe the case of a 73-year-old man who experienced dry cough and exertional dyspnea after dabigatran administration. Chest radiographs revealed the development of bilateral consolidative and ground glass opacity, and transbronchial lung biopsy showed organized materials in the alveolar spaces with moderate inflammatory infiltrate and focal fibrosis. Lung opacity gradually disappeared after discontinuing dabigatran. To date, there has been only one report regarding dabigatran-induced lung injury, except for alveolar hemorrhage and eosinophilic pneumonia. Therefore, we should consider that any drug can cause various types of lung injuries.
Keywords: BALF, Bronchoalveolar lavage fluid; Dabigatran; Drug-induced lung injury; HRCT, high-resolution computed tomography; Interstitial pneumonia; NSIP, nonspecific interstitial pneumonia; OP, organizing pneumonia.