Deuterated Drug Molecules: Focus on FDA-Approved Deutetrabenazine Published as part of the Biochemistry series "Biochemistry to Bedside"

Biochemistry. 2018 Feb 6;57(5):472-473. doi: 10.1021/acs.biochem.7b00765. Epub 2017 Nov 21.
No abstract available

MeSH terms

  • Adrenergic Uptake Inhibitors / adverse effects
  • Adrenergic Uptake Inhibitors / chemistry*
  • Adrenergic Uptake Inhibitors / metabolism
  • Adrenergic Uptake Inhibitors / therapeutic use
  • Animals
  • Biochemistry / methods
  • Chorea / drug therapy
  • Deuterium / adverse effects
  • Deuterium / chemistry*
  • Deuterium / metabolism
  • Deuterium / therapeutic use
  • Drug Approval* / methods
  • Drug Discovery* / methods
  • Drug and Narcotic Control / methods
  • Humans
  • Tardive Dyskinesia / drug therapy
  • Tetrabenazine / adverse effects
  • Tetrabenazine / analogs & derivatives*
  • Tetrabenazine / chemistry
  • Tetrabenazine / metabolism
  • Tetrabenazine / therapeutic use

Substances

  • Adrenergic Uptake Inhibitors
  • Deuterium
  • deutetrabenazine
  • Tetrabenazine