The amazing brain drain

J Exp Med. 2017 Dec 4;214(12):3469-3470. doi: 10.1084/jem.20172031. Epub 2017 Nov 21.


In this issue of JEM, Antila et al. ( demonstrate that central nervous system lymphatics develop in the mouse meninges during early postnatal periods and display remarkable plasticity in adult periods through manipulation of VEGF-C-VEGFR3 signaling.

Publication types

  • Comment

MeSH terms

  • Animals
  • Central Nervous System
  • Glymphatic System*
  • Lymphatic Vessels*
  • Mice
  • Signal Transduction
  • Vascular Endothelial Growth Factor C


  • Vascular Endothelial Growth Factor C