Gene activation in human cells using CRISPR/Cpf1-p300 and CRISPR/Cpf1-SunTag systems

Protein Cell. 2018 Apr;9(4):380-383. doi: 10.1007/s13238-017-0491-6.

Authors

Xin Zhang¹, Wei Wang¹, Lin Shan¹, Le Han¹, Shufeng Ma¹, Yan Zhang¹, Bingtao Hao¹, Ying Lin², Zhili Rong³

Affiliations

¹ Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
² Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China. linying0216@smu.edu.cn.
³ Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China. rongzhili@smu.edu.cn.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Bacterial Proteins / genetics*
CRISPR-Cas Systems / genetics
Endonucleases / genetics*
Gene Editing
HEK293 Cells
Humans
Transcriptional Activation / genetics*
p300-CBP Transcription Factors / genetics*

Substances

Bacterial Proteins
p300-CBP Transcription Factors
Cas12a protein
Endonucleases