Home oxygen therapy for chronic lung disease in extremely low-birth-weight infants

Am J Dis Child. 1989 Mar;143(3):357-60. doi: 10.1001/archpedi.1989.02150150115028.

Abstract

Chronic lung disease that requires prolonged oxygen therapy commonly complicates the recovery of extremely low-birth-weight infants (less than 1000 g). We report follow-up data through 18.5 +/- 0.9 (mean +/- SEM) months of age in 30 extremely low-birth-weight infants (birth weight, 783 +/- 24 g; gestational age, 26.0 +/- 0.3 weeks) who were discharged home receiving supplemental oxygen. Oxygen was prescribed to maintain arterial oxygen saturation at 95% or greater. At discharge, postconceptional age was 40.5 +/- 0.6 weeks, and weight was 2220 +/- 50 g. Duration of home oxygen therapy was 4.5 +/- 0.5 months. The mean weight percentile increased from less than 5 to 23 between discharge and the last follow-up. All infants survived; only 6 required hospitalization for acute medical illnesses. We conclude that carefully supervised home oxygen therapy permits the safe early discharge of selected extremely low-birth-weight infants with chronic lung disease.

MeSH terms

  • Body Weight
  • Child Development / physiology
  • Chronic Disease
  • Female
  • Follow-Up Studies
  • Gestational Age
  • Home Nursing*
  • Humans
  • Infant, Low Birth Weight*
  • Infant, Newborn
  • Lung Diseases / complications
  • Lung Diseases / physiopathology
  • Lung Diseases / therapy*
  • Male
  • Oxygen Inhalation Therapy*
  • Prospective Studies