Towards re-purposing BH3-mimetics in Legionella and viral infections

Expert Rev Anti Infect Ther. 2017 Dec;15(12):1071-1073. doi: 10.1080/14787210.2017.1409621. Epub 2017 Nov 29.
No abstract available

Keywords: BCL-XL; Legionella; apoptosis; host-targeted antimicrobials; macrophage.

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology*
  • Antiviral Agents / chemistry
  • Antiviral Agents / pharmacology*
  • Humans
  • Legionellosis / drug therapy
  • Peptide Fragments / chemistry*
  • Peptidomimetics / chemistry
  • Peptidomimetics / pharmacology*
  • Proto-Oncogene Proteins / chemistry*
  • Virus Diseases / drug therapy

Substances

  • Anti-Bacterial Agents
  • Antiviral Agents
  • Bax protein (53-86)
  • Peptide Fragments
  • Peptidomimetics
  • Proto-Oncogene Proteins