Use of factor concentrates for the management of perioperative bleeding: guidance from the SSC of the ISTH

J Thromb Haemost. 2018 Jan;16(1):170-174. doi: 10.1111/jth.13893. Epub 2017 Nov 23.

Authors

A Godier¹, A Greinacher², D Faraoni³, J H Levy⁴, C M Samama⁵

Affiliations

¹ Department of Anesthesiology and Intensive Care Medicine, Fondation Adolphe de Rothschild and INSERM UMRS-1140 Faculté de Pharmacie, Descartes University, Paris, France.
² Department of Immunology and Transfusion Medicine, Universitätsmedizin Greifswald, Greifswald, Germany.
³ Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Canada.
⁴ Departments of Anesthesiology, Surgery, and Critical Care, Duke University School of Medicine, Durham, NC, USA.
⁵ Department of Anesthesiology and Intensive Care Medicine, Assistance Publique-Hôpitaux de Paris, Cochin University Hospital, Paris Descartes University, Paris, France.

PMID: 29168325
DOI: 10.1111/jth.13893

No abstract available

Publication types

Practice Guideline
Review

MeSH terms

Blood Coagulation Factors / adverse effects
Blood Coagulation Factors / standards
Blood Coagulation Factors / therapeutic use*
Blood Loss, Surgical / prevention & control*
Consensus
Evidence-Based Medicine / standards*
Factor VIIa / adverse effects
Factor VIIa / standards
Factor VIIa / therapeutic use*
Factor XIII / adverse effects
Factor XIII / standards
Factor XIII / therapeutic use*
Fibrinogen / adverse effects
Fibrinogen / standards
Fibrinogen / therapeutic use*
Hemostatics / adverse effects
Hemostatics / standards
Hemostatics / therapeutic use*
Humans
Postoperative Hemorrhage / blood
Postoperative Hemorrhage / diagnosis
Postoperative Hemorrhage / drug therapy*
Recombinant Proteins / therapeutic use
Risk Factors
Treatment Outcome

Substances

Blood Coagulation Factors
Hemostatics
Recombinant Proteins
prothrombin complex concentrates
Fibrinogen
Factor XIII
Factor VIIa