Cardiorespiratory Fitness and Health Outcomes: A Call to Standardize Fitness Categories

Mayo Clin Proc. 2018 Mar;93(3):333-336. doi: 10.1016/j.mayocp.2017.10.011. Epub 2017 Nov 22.


An inverse association between physical activity or fitness status and health outcomes has been reported by several cohort studies. When fitness categories are established in quartiles or quintiles based on the peak exercise capacity achieved, the association is graded. Although significant health benefits of increased cardiorespiratory fitness (CRF) have been uniformly reported, the degree of protection has varied substantially between studies. This variability is likely due to varying methods used to define CRF categories, and not considering age, despite its strong effect on CRF. To ameliorate these methodological discrepancies, we propose standardized guidelines by which age-specific CRF categories should be defined.

MeSH terms

  • Age Factors*
  • Cardiorespiratory Fitness*
  • Female
  • Guidelines as Topic
  • Humans
  • Male
  • Metabolic Equivalent*
  • Reference Standards