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Review
, 40 (11), 814-822

Advances Towards Controlling Meiotic Recombination for Plant Breeding

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Review

Advances Towards Controlling Meiotic Recombination for Plant Breeding

Kyuha Choi. Mol Cells.

Abstract

Meiotic homologous recombination generates new combinations of preexisting genetic variation and is a crucial process in plant breeding. Within the last decade, our understanding of plant meiotic recombination and genome diversity has advanced considerably. Innovation in DNA sequencing technology has led to the exploration of high-resolution genetic and epigenetic information in plant genomes, which has helped to accelerate plant breeding practices via high-throughput genotyping, and linkage and association mapping. In addition, great advances toward understanding the genetic and epigenetic control mechanisms of meiotic recombination have enabled the expansion of breeding programs and the unlocking of genetic diversity that can be used for crop improvement. This review highlights the recent literature on plant meiotic recombination and discusses the translation of this knowledge to the manipulation of meiotic recombination frequency and location with regards to crop plant breeding.

Keywords: breeding; crossover; epigenetics; meiotic DSBs; meiotic recombination.

Figures

Fig. 1
Fig. 1. Genome-wide meiotic DSB map in a plant
(A) Production of the SPO11-1 protein-DNA oligonucleotide complex during meiotic DSB formation. (B) Landscapes of SPO11-1-oligonucletides (oligos) and crossovers along Arabidopsis chromosome 1. (C) Representative snap shots for meiotic DSBs, nucleosome occupancy, and H3K4m3 levels, in the chromosomal arm and centromeric region of Arabidopsis chromosome 1. A DNA transposon, Helitron (AT1TE29920) located at a gene promoter displays high DSB levels and low nucleosome occupancy (left image), while centromeric transposons (AT1TE51615, AT1TE51645, Gypsy retrotransposon) display low levels of DSBs (right image).
Fig. 2
Fig. 2. Control of crossover frequency and location in plant genomes
(A) Limitation of crossover number in the Arabidopsis genome. During Arabidopsis male meiosis, an average of 250 meiotic DSBs and 11 crossovers occur throughout the genome. (B) A strategy for plant breeding programs to increase crossovers in both euchromatin and heterochromatin of hybrid lines by genetic and epigenetic disruptions. Enhancing the number of crossovers in the genome helps accelerate genetic mapping of desirable traits and generation of new varieties.

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