Comment
doi: 10.1038/nrd.2017.241.
Obesity: GDF15 tells the brain to lose weight
- PMID: 29180731
- DOI: 10.1038/nrd.2017.241
Item in Clipboard
Comment
Obesity: GDF15 tells the brain to lose weight
Nat Rev Drug Discov.
.
No abstract available
Comment on
-
Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys.Sci Transl Med. 2017 Oct 18;9(412):eaan8732. doi: 10.1126/scitranslmed.aan8732. Sci Transl Med. 2017. PMID: 29046435
Similar articles
-
GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates.Nat Med. 2017 Oct;23(10):1150-1157. doi: 10.1038/nm.4392. Epub 2017 Aug 28. Nat Med. 2017. PMID: 28846097
-
GDF15 deficiency promotes high fat diet-induced obesity in mice.PLoS One. 2018 Aug 2;13(8):e0201584. doi: 10.1371/journal.pone.0201584. eCollection 2018. PLoS One. 2018. PMID: 30070999 Free PMC article.
-
Treatment with the TGF-b superfamily cytokine MIC-1/GDF15 reduces the adiposity and corrects the metabolic dysfunction of mice with diet-induced obesity.Int J Obes (Lond). 2018 Mar;42(3):561-571. doi: 10.1038/ijo.2017.258. Epub 2017 Dec 5. Int J Obes (Lond). 2018. PMID: 29026214
-
Uniting GDF15 and GFRAL: Therapeutic Opportunities in Obesity and Beyond.Trends Endocrinol Metab. 2018 Aug;29(8):560-570. doi: 10.1016/j.tem.2018.05.002. Epub 2018 Jun 1. Trends Endocrinol Metab. 2018. PMID: 29866502 Review.
-
Anorexia-cachexia and obesity treatment may be two sides of the same coin: role of the TGF-b superfamily cytokine MIC-1/GDF15.Int J Obes (Lond). 2016 Feb;40(2):193-7. doi: 10.1038/ijo.2015.242. Epub 2015 Dec 1. Int J Obes (Lond). 2016. PMID: 26620888 Review.
Cited by
-
Evaluation of GDF15 as a therapeutic target of cardiometabolic diseases in human: A Mendelian randomization study.EBioMedicine. 2019 Mar;41:85-90. doi: 10.1016/j.ebiom.2019.02.021. Epub 2019 Feb 13. EBioMedicine. 2019. PMID: 30772304 Free PMC article.
-
Interactions Between Weight Loss and Plasma Neurodegenerative Markers for Determining Cognitive Decline Among Community-Dwelling Older Adults.J Gerontol A Biol Sci Med Sci. 2022 Jun 1;77(6):1159-1168. doi: 10.1093/gerona/glac015. J Gerontol A Biol Sci Med Sci. 2022. PMID: 35034116 Free PMC article.
-
RET Receptor Tyrosine Kinase: Role in Neurodegeneration, Obesity, and Cancer.Int J Mol Sci. 2020 Sep 26;21(19):7108. doi: 10.3390/ijms21197108. Int J Mol Sci. 2020. PMID: 32993133 Free PMC article. Review.
-
Elevated serum growth differentiation factor 15 in multiple system atrophy patients: A case control study.World J Clin Cases. 2020 Jun 26;8(12):2473-2483. doi: 10.12998/wjcc.v8.i12.2473. World J Clin Cases. 2020. PMID: 32607324 Free PMC article.
-
Integrated analyses of growth differentiation factor-15 concentration and cardiometabolic diseases in humans.Elife. 2022 Aug 2;11:e76272. doi: 10.7554/eLife.76272. Elife. 2022. PMID: 35916366 Free PMC article.
References
-
- Sci Transl Med. 2017 Oct 18;9(412):null - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
