Myriads: P-value-based multiple testing correction

Bioinformatics. 2018 Mar 15;34(6):1043-1045. doi: 10.1093/bioinformatics/btx746.

Abstract

Motivation: There are many multiple testing correction methods. Some of them are robust to various dependencies in the data while others are not. Some of the implementations have problems for managing high dimensional list of P-values as currently demanded by microarray and other omic technologies.

Results: The program Myriads, formerly SGoF+, provides some of the most important P-value-based correction methods jointly with a test of dependency and a P-value simulator. Myriads easily manage hundreds of thousands of P-values.

Availability and implementation: http://myriads.webs.uvigo.es.

Contact: myriads@uvigo.es.

Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computational Biology / methods
  • Software*