Outcome of ankle arthrodesis and ankle prosthesis: a review of the current status

Br Med Bull. 2017 Dec 1;124(1):91-112. doi: 10.1093/bmb/ldx042.


Introduction: In advanced stages of ankle osteoarthritis (OA), ankle arthrodesis (AA) or total ankle arthroplasty (TAR) may be necessary. Our purpose is to compare AA and total ankle replacement for the surgical management of end stage ankle OA.

Sources of data: We conducted a literature search of PubMed, Medline, CINAHL, Cochrane, Embase and Google Scholar databases using the terms 'ankle' in combination with 'OA', 'arthrodesis', 'arthroplasty', 'joint fusion', 'joint replacement'. Studies where treatment was exclusively total ankle replacement or AA were excluded. Treatment characteristics and outcome parameters (overall postoperative outcome and complication rate) were reviewed.

Areas of agreement: When counseling patients who are considering their options with regard to ankle arthritis treatment, surgeons should determine on an individual basis which procedure is more suitable.

Areas of controversy: TAR has become an accepted treatment for end-stage OA, but revision rates for TAR are significant higher than for AA (odds ratio 2.28 95% confidence interval [CI], 1.63-3.19; P < 0.0001).

Growing points: The results of TAA are gradually improving, but the procedure cannot yet be recommended for the routine management of ankle OA.

Areas timely for developing research: Although there is some evidence to support TAR to conserve ankle motion and offer improved function and decreased pain with high satisfaction rates, revision rates for TAR are significantly higher than revision rates for AA. Proper patient selection should be better addressed in future studies for successful treatment of end-stage ankle OA.

Level of evidence: Systematic review, level III.

Keywords: Ankle osteoarthritis; ankle arthrodesis; ankle arthroplasty; ankle joint fusion; ankle joint replacement.

Publication types

  • Comparative Study
  • Review
  • Systematic Review

MeSH terms

  • Ankle Joint / physiopathology*
  • Ankle Joint / surgery
  • Arthrodesis*
  • Arthroplasty, Replacement, Ankle*
  • Humans
  • Joint Prosthesis
  • Osteoarthritis / complications
  • Osteoarthritis / physiopathology
  • Osteoarthritis / surgery*
  • Postoperative Complications / physiopathology*
  • Range of Motion, Articular / physiology
  • Treatment Outcome
  • Weight-Bearing / physiology