How Cryo-EM Became so Hot

Yifan Cheng; Robert M Glaeser; Eva Nogales

doi:10.1016/j.cell.2017.11.016

How Cryo-EM Became so Hot

Cell. 2017 Nov 30;171(6):1229-1231. doi: 10.1016/j.cell.2017.11.016.

Authors

Yifan Cheng¹, Robert M Glaeser², Eva Nogales³

Affiliations

¹ Department of Biochemistry and Biophysics, and Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.
² Lawrence Berkeley National Laboratory, Berkeley, CA, USA. Electronic address: rmglaeser@lbl.gov.
³ Lawrence Berkeley National Laboratory, Berkeley, CA, USA; Department of Molecular and Cell Biology, and Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA.

Abstract

The Royal Swedish Academy of Sciences awarded the 2017 Nobel Prize for Chemistry to Jacques Dubochet, Joachim Frank, and Richard Henderson for "developing cryoelectron microscopy for the high-resolution structure determination of biomolecules in solution." Achieving this goal, which required innovation, persistence, and uncommon physical insight, has broadened horizons for structural studies in molecular and cell biology.

Publication types

Biography
Historical Article

MeSH terms

Chemistry / history*
Cryoelectron Microscopy*
History, 20th Century
History, 21st Century
Nobel Prize*
Proteins / chemistry

How Cryo-EM Became so Hot

Authors

Affiliations

Abstract

Publication types

MeSH terms

Substances

Personal name as subject

Grants and funding