Cutaneous anaplastic large cell lymphoma in a multiple sclerosis patient receiving Fingolimod

Mult Scler Relat Disord. 2018 Jan:19:121-123. doi: 10.1016/j.msard.2017.11.012. Epub 2017 Nov 22.


Background: Previous reports of cutaneous neoplastic lesions secondary to Fingolimod treatment among multiple sclerosis patients.

Objective: Reporting a case of cutaneous large cell lymphoma in a multiple sclerosis patient during Fingolimod treatment.

Method: Case study.

Result: Our patient developed CD30+ cutaneous large cell lymphoma two years after initiation of Fingolimod treatment and her symptoms regressed following the cessation of treatment.

Conclusion: This report indicates that cutaneous lymphoid neoplasms should be considered a possible side effect among patients receiving Fingolimod.

Keywords: Cutaneous large cell lymphoma; Fingolimod; Multiple sclerosis; Side effect.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Fingolimod Hydrochloride / adverse effects*
  • Humans
  • Immunosuppressive Agents / adverse effects*
  • Lymphoma, Large-Cell, Anaplastic / chemically induced*
  • Multiple Sclerosis / drug therapy*


  • Immunosuppressive Agents
  • Fingolimod Hydrochloride