Population screening for plasma cholesterol: community-based results from Connecticut

Am Heart J. 1989 Mar;117(3):649-56. doi: 10.1016/0002-8703(89)90741-2.


Plasma cholesterol levels were measured in 15,892 participants of a cholesterol screening in Hartford, Connecticut. The screenees were typically health conscious as evidenced by the low prevalence of current cigarette smoking (12%). However, more than 25% of the men and 35% of the women over the age of 50 years had cholesterol levels in excess of 240 mg/dl, placing them at moderate to high risk for coronary artery disease. Results showed a pronounced dose-response relationship between cigarette smoking and cholesterol levels in men of all age groups and in women of premenopausal age; however, average cholesterol levels were similar in exsmokers and subjects who had never smoked. Risk analysis revealed a strong positive association between cholesterol and prevalence of nonfatal myocardial infarctions. Notably patients with newly diagnosed hypercholesterolemia reduced their cholesterol levels an average of 40 mg/dl under the care of a physician. These results indicate that cholesterol screening coupled with physician follow-up and treatment can have a substantial impact in lowering cholesterol levels and the attendant risk of cardiovascular disease.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Cholesterol / blood*
  • Connecticut
  • Coronary Disease / prevention & control
  • Female
  • Follow-Up Studies
  • Humans
  • Hypercholesterolemia / prevention & control*
  • Male
  • Mass Screening*
  • Middle Aged
  • Myocardial Infarction / prevention & control
  • Risk Factors
  • Sex Factors


  • Cholesterol